Prof. Dr. Aygül Demirol

LASER METHOD

In the IVF (In Vitro Fertilization) – microinjection method, laser can be used in various ways. There are three main areas of use.

To summarize briefly:

– Assisted hatching (commonly known as thinning or opening a window in the embryo wall): It can be performed using laser. With laser technique, the embryo shell can be thinned or perforated without damaging the embryo, and in this way an attempt is made to increase the embryo’s implantation in the uterus. A very important point here is that the laboratory specialist performing the procedure must be highly competent in the use of laser. Inappropriate application may cause serious damage to the embryo and have a negative effect by reducing pregnancy rates.

– Performing a biopsy from the embryo for genetic analysis, that is, taking a cell (for PGD & PGS procedures): With the help of laser, an opening that will not damage the embryo is created, and one or two cells that represent/sample the embryo are removed. These are analyzed by the genetics department and healthy embryos are transferred. The use of laser in this procedure provides great convenience. As with every technique, it must be performed by experienced hands.

– Performing microinjection with the help of laser: The ICSI procedure, that is, the microinjection itself, can be carried out with laser if the patient’s criteria are suitable. This system is applied on an individualized basis. The aim is to reduce the rate of egg degeneration after the procedure.

In her scientific studies, Assoc. Prof. Dr. Aygül Demirol has shown that, in women aged 35 and over and in women who have not been able to conceive despite previous ICSI (microinjection) applications, the use of laser systems during fertilization of the eggs by microinjection increases fertilization rates, improves embryo quality and positively affects pregnancy rates. She has published on this subject and given presentations at congresses. Considering the advantages and convenience provided by the use of laser in genetic diagnosis and assisted hatching techniques, and its superiority in these areas, it should be widely used in our suitable patients.

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