Prof. Dr. Aygül Demirol

IMSI

IMSI (high magnification ICSI = high magnification microinjection)

It is a highly effective method that has been introduced into practice for infertile couples with severe male factor. This is a new technique and is performed only in centers that have an IMSI microscope and by specialists trained in this field. Although it is new, its results have been clearly evaluated and its effectiveness has been proven. It allows the sperm to be used in the microinjection procedure to be examined by enlarging it thousands of times with the most advanced technological means, thus enabling the selection of the best sperm. A special microscope is used for this procedure. 

In the microinjection procedure, each mature female egg is fertilized with a single sperm. Egg and sperm quality determine embryo quality. The selection of the sperm to be used for fertilization is therefore of vital importance. If the sperm with the best fertilization capacity and the highest genetic quality is selected, the fertilization rate in the procedure is high, embryo quality is high, pregnancy rates are high, and pregnancy loss rates are low.

IMSI is used in cases with severe sperm problems and in couples with recurrent IVF (In Vitro Fertilization) failure. In a standard microinjection system, sperm are selected at a magnification of 100 to 400 times. In high magnification microinjection, that is IMSI, sperm can be magnified up to 1600 to 7000 times, examined in great detail with meticulous evaluation of certain features of the sperm head, then selected and used for microinjection.

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